There is no good test, but symptoms can point you in the right direction. Early on these pateints have CNS findings, tinnitus, headaches, menengial signs, and fever. This is followed by skin and hair findings.
Ocular findings include a cherry red disk, exudative detachments (with the fluid often forming around the optic nerve). Late retinal findings include pigment changes, a “sunset glow” fundus, and subretinal neovascular membranes.
An FA workup includes early pinpoint hyperfluorescences with late subretinal pooling and disk leakage (findings look similar to posterior scleritis).